William DuMouchel, PhD

Szarfman organizes a virtual meeting on a new safety data mining methodology designed by DuMouchel.

Menschik and Baer exchange about classic data mining references written by Szarfman and DuMouchel.

Szarfman raises COVID-19 vaccine safety monitoring concerns with CBER Director Marks.

Szarfman presents RGPS to Marks and other CBER officials, calling MGPS not state of the art.

Szarfman shares DuMouchel's RGPS analysis showing 49 examples of extreme masking with senior FDA officials.

DuMouchel sends analysis adjusting for the fact that 99% of 2021 VAERS reports are for COVID-19 vaccines.

Niu asks whether DuMouchel's findings affect 2021 data mining results; Szarfman confirms they do.

Niu forwards DuMouchel's analysis to Zinderman without Szarfman; Zinderman flags it as worth considering.

Baer welcomes DuMouchel's input; Menschik pushes back on reaching out to Szarfman directly.

Szarfman shares DuMouchel's RGPS analysis revealing six new statistically significant safety signals.

Szarfman resends RGPS analysis flagging cardiac signals; Niu tells her CBER cannot collaborate.

Szarfman circulates analysis showing MGPS undervalued acute myocardial infarction signals for Pfizer and Moderna.

Szarfman receives clearance from Stockbridge to publish her paper on masking and RGPS.

Szarfman resends RGPS analysis on acute myocardial infarction and invites Forshee to collaborate.

Szarfman writes Forshee that RGPS shows statistically significant mortality signals for Pfizer and Moderna vaccines.

Forshee forwards Szarfman's mortality findings to Marks, expressing concern about her interpretation.

Walinsky circulates Szarfman's preprint to FDA officials weighing Moderna's pediatric COVID-19 vaccine appeal.

Szarfman, DuMouchel, and co-authors publish 'Signaling COVID-19 Vaccine Adverse Events' in Drug Safety.

FDA officials discuss the masking effect three years after Szarfman raised it; Baer points to her published paper.

Baer tells Menschik RGPS yields significantly higher signals than MGPS; Menschik concurs but prefers to keep MGPS.